BrainLab: Imaging

When citing the basic tissue segmentation, please reference:

Kovacevic, N., Lobaugh, N.J., Bronskill, M.J., Vevine, B., Feinstein, A., Black, S.E. (2002). A robust method for extraction and automatic segmentation of brain images. NeuroImage, 17, 1087-1100.

When citing the SABRE pipeline, please reference:

Dade, L.A., Gao, F.Q., Kovacevic, N., Roy, P., Rockel, C., O'Toole, C.M., Lobaugh, N.J., Feinstein, A., Levine, B., Black, S.E.(2004). Semiautomatic brain region extraction: a method of parcellating brain regions from structural magnetic resonance images. NeuroImage, 22, 1492-1502.

When citing Lesion Explorer, please reference:

Ramirez, J., Gibson, E., Quddus, A., Lobaugh, N.J., Feinstein, A., Levine, B., Scott, C.J.M., Levy-Cooperman, N., Gao, F.Q., Black, S.E. (2011) Lesion explorer: a comprehensive segmentation and parcellation package to obtain regional volumetrics for subcortical hyperintensities and intracranial tissue. NeuroImage, 54(2), 963-973.

For Lesion Explorer reliability, please see:

Ramirez, J., Scott, C.J., Black, S.E. (2013). A short-term scan-rescan reliability text measuring brain tissue and subcortical hyperintensity volumetrics obtained using the lesion exploer structural MRI processing pipeline. Brain Topography, 26(1), 35-8.

For the importance of lesion segmentation, please see:

Levy-Cooperman, N., Ramirez, J., Lobaugh, N.J., Black, S.E. (2008). Misclassified tissue volumes in alzheimer disease patients with white matter hyperintensities: importance of lesion segmentation procedures for volumetric analysis. Stroke, 39, 1134-1141.

When citing FLEX, please reference:

Gibson, E., Gao, F.Q., Black, S.E., Lobaugh, N.J. (2010). Automatic segmentation of white matter hyperintensities in the elderly using FLAIR images at 3T. Journal of Magnetic Resonance Imaging, 31, 1311-1322.